| Name | : Bonifasia Junita Anugrahani |
| Student Number | : 18/431475/TP/12331 |
| Program Studi | : S1 Teknologi Pangan dan Hasil Pertanian |
| : bonifasia.junita@mail.ugm.ac.id | |
| : https://www.linkedin.com/in/bonifasia-junita/ | |
| Final Project Title | : Antifungal Activity of Fungus Comb Extracts from Indo-Malayan Termite Macrotermes gilvus Hagen Mound Against Aspergillus flavus FNCC 6181 |
| Deskripsi | : Food security, which includes food availability, access, utilization, and stability, is an important human need that has to be fulfilled in order to provide a good quality of life. The challenge in providing healthy, nutritious, and safe food is to prevent pre- and postharvest losses due to the contamination by microorganisms, including fungi Aspergillus sp., especially A. flavus. This study is aimed to investigate the alternative natural source antifungal agent by determining the antifungal activity of fungus comb extracted from Indo-Malayan Termite Macrotermes gilvus Hagen (Isoptera: Termitidae) against Aspergillus flavus FNCC 6181. Fungus comb extraction was carried out gradually using n-hexane, ethyl acetate, methanol, and water solvents. Having nystatin as a positive control, the susceptibility test was done through the Kirby-Bauer method on PDA medium. The fungus comb extracts were also determined for their MIC on RPMI 1640 and MFC on PDA medium. The results showed that the highest inhibition activity was presented by ethyl acetate extract and the most effective dose was 50 mg; as proved by the diameter of the inhibition zone that was 49.33 ������± 13.43 mm and also the lowest MIC and MFC 0.78 mg/mL and 1.56 mg/mL, respectively. Regarding this, the fungus comb extracted with ethyl acetate had the potential to be an antifungal agent. However, the application of this extract as a food antifungal agent needs to be further investigated. |